A.B. Molecular Biology

MOL 110 Neuroscience and Everyday Life (See NEU 101)

MOL 211 Life on Earth: Chaos and Clockwork of Biological Design (See EEB 211)

MOL 214 Introduction to Cellular and Molecular Biology (also

EEB 214

MOL 215 Quantitative Principles in Cell and Molecular Biology (also

EEB 215

MOL 231 An Integrated, Quantitative Introduction to the Natural Sciences I (See ISC 231)

MOL 232 An Integrated, Quantitative Introduction to the Natural Sciences I (See ISC 232)

MOL 233 An Integrated, Quantitative Introduction to the Natural Sciences II (See ISC 233)

MOL 234 An Integrated, Quantitative Introduction to the Natural Sciences II (See ISC 234)

MOL 327 Immune Systems: From Molecules to Populations (See EEB 327)

MOL 340 Molecular and Cellular Immunology Spring STN A broad survey of the field of immunology and the mammalian immune system. The cellular and molecular basis of innate and acquired immunity will be discussed in detail. The course will provide frequent exemplars drawn from human biology in health and disease. Prerequisite: MOL214. A. Ploss

MOL 342 Genetics Spring STN Basic principles of genetics illustrated with examples from prokaryote and eukaryote organisms. Classical genetic techniques as well as molecular and genomic approaches will be discussed. The evolving concept of the gene, of genetic interactions and gene networks, as well as chromosome mechanics will be the focus of the course. Selected topics will include gene regulation, cancer genetics, the human biome, imprinting, and stem cells. Two 90-minute lectures, one precept. Prerequisite: MOL 214 or permission of instructor. M. Abou Donia, M. Levine

MOL 345 Biochemistry (also

CHM 345

MOL 348 Cell and Developmental Biology Spring STN The course will investigate the roles that gene regulation, cell-cell communication, cell adhesion, cell motility, signal transduction and intracellular trafficking play in the commitment, differentiation and assembly of cells into specialized tissues. The mechanisms that underlie development of multicellular organisms, from C. elegans to humans, will be examined using biochemical, genetic and cell biological approaches. In-class problem solving, group work, and active learning approaches will be used to emphasize key concepts and analyze experimental data. Two 90-minute lectures, one precept. Prerequisite: MOL 214. R. Burdine, D. Devenport

MOL 350 Laboratory in Molecular Biology Fall STL MOL350 prepares students to become contributing members of a research lab. Students will advance as creative, critical thinkers and effective communicators. While completing original research, students will employ techniques used by cell and molecular biologists, molecular geneticists, and biochemists. Students will discover how and why specific knowledge, skills and techniques are applied to the semester's research topic; will practice extracting pertinent information from scientific literature; and will generate a research report modeled on the scientific literature. One lecture, two three-hour laboratories. Prerequisite: MOL 214. J. Schottenfeld-Roames

MOL 380 Modern Microbiology Fall STN Microbes offer a rich world for exploration, a teeming universe invisible to the naked eye but thrilling in terms of diversity and scope. Human beings could not survive in their absence, yet we often think of them as the enemy. In fact, the majority are beneficial and can be harnessed for good in science and industry. This course will examine both sides: first an overview of microbial growth and function as well as specialized applications in areas such as photosynthesis, synthetic biology, quorum sensing, and CRISPR, with subsequent study of the threats to human health arising from dangerous pathogens that cause bacterial and viral disease. M. Jonikas

MOL 408 Cellular and Systems Neuroscience (See NEU 408)

MOL 410 Introduction to Biological Dynamics Not offered this year STN Designed for students in the biological sciences, this course focuses on the application of mathematical methods to biological problems. Intended to provide a basic grounding in mathematical modeling and data analysis for students who might not have pursued further study in mathematics. Topics include differential equations, linear algebra, difference equations, and probability. Each topic will have a lecture component and computer laboratory component. Students will work extensively with the computing package MATLAB. No previous computing experience necessary. Two 90-minute lectures, one laboratory. N. Wingreen, T. Gregor

MOL 425 Infection: Biology, Burden, Policy (also

WWS 355

MOL 433 Biotechnology (also

CBE 434

MOL 435 Pathogenesis and Bacterial Diversity Not offered this year An examination of current topics exploring the microbial world with emphasis on signal transduction, and the molecular basis for bacterial diversity and their roles in bacterial pathogenesis. Topics will include the regulation of cell division and sporulation, quorum sensing, mechanisms of microbial differentiation, evolution of communicable diseases, molecular mechanisms of pathogenesis, and identification of virulence factor and immunization. Two lectures, one precept. Prerequisites: MOL214 or permission of instructor. Staff

MOL 437 Computational Neuroscience (See NEU 437)

MOL 438 Biomolecular Engineering (See CBE 438)

MOL 440 Genome Integrity and Human Disease Not offered this year STN This course deals with the basic science that led to the molecular understanding of human diseases associated with defects in genome maintenance, such as aging and cancer. The first two-thirds of each class is a group discussion of an assigned paper. The last third is a lecture-type introduction to the material for the next class. Topics include telomeres, trinucleotide repeats, fragile sites, transcriptional sources of genome instability, and massive genome rearrangements.Two 90-minute seminars. V. Zakian

MOL 447 Neuroimmunology: Immune Molecules in Normal Brain Function and Neuropathology (See NEU 447)

MOL 450 Stem Cells and Cell Fate Decision Processes in the Genomic Era Not offered this year Focuses on the current state of stem cell research and the future directions for this field. Stem cell research has great promise for the future of regenerative medicine. Very little is known about the molecular biology that underlies stem cell fate determination. The completion of the human and mouse genome sequences, together with novel technologies to observe global gene expression, offer unique opportunities to unravel stem cell regulatory mechanisms. Explores parallels to other, more mature biological systems. Two lectures, one preceptorial. Prerequisite: 342 and 348, or instructor's permission. Staff

MOL 455 Introduction to Genomics and Computational Molecular Biology (See QCB 455)

MOL 459 Viruses: Strategy and Tactics (also

GHP 459

MOL 460 Diseases in Children: Causes, Costs, and Choices (also

STC 460

MOL 470 Advanced Topics in Genetic Analysis Not offered this year STN The application of current tools of human genetics and genomic analysis including SNPs, copy number variants, HapMaps, high throughput DNA sequencing and DNA microarrays to perform genome-wide association studies of complex traits with an emphasis on neurological diseases including autism and schizophrenia. Covers recent evolution within the human species and genetic divergence of human populations in response to selective forces. Extensive use will be made of online genome databases as interactive tools for genome analysis. One three-hour seminar. Prerequisite: MOL 342. Staff

MOL 981 Junior Independent Work Fall No Description Available Staff