Biochemistry and pharmacology of synaptic transmission
Bachelor's degree
In Maynard (USA)
Description
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Type
Bachelor's degree
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Location
Maynard (USA)
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Start date
Different dates available
This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. We focus on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); we also examine amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems and ion fluxes that they control. The involvement of particular neurotransmitters in human diseases is considered.
Facilities
Location
Start date
Start date
Reviews
Subjects
- Systems
- Biochemistry
- Pharmacology
Course programme
Lectures: 2 sessions / week, 1.5 hours / session
Recitations: 1 session / week, 1.5 hours / session
This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. We focus on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); we also examine amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems and ion fluxes that they control. The involvement of particular neurotransmitters in human diseases is considered.
Cooper, Jack R., Floyd E. Bloom, and Robert H. Roth. The Biochemical Basis of Neuropharmacology. 8th ed. Oxford, UK: Oxford University Press, 2002. ISBN: 9780195140088.
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Biochemistry and pharmacology of synaptic transmission