Chemistry of biomolecules i
Master
In Maynard (USA)
Description
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Type
Master
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Location
Maynard (USA)
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Start date
Different dates available
5.451 is a half-semester introduction to natural product biosynthetic pathways. The course covers the assembly of complex polyketide, peptide, terpene and alkaloid structures. Discussion topics include chemical and biochemical strategies used to elucidate natural product pathways.
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Course programme
Lectures: Two sessions / week, 1.5 hours / session
The course is primarily based on recent scientific literature, but these books may provide helpful background.
Dewick, Paul M. Medicinal Natural Products: A Biosynthetic Approach. 2nd ed. New York, NY: John Wiley & Sons, Inc., 2001. ISBN: 9780471496410 (paperback); ISBN: 9780471496403 (hardcover).
Silverman, Richard B. The Organic Chemistry of Enzyme-Catalyzed Reactions. San Diego, CA: Academic Press, 2002. ISBN: 9780126437317.
It is expected that students will maintain the highest standards of academic honesty.
With respect to homework assignments, it is expected that no student will turn in work that is not his or her own by copying the work of another student or by using the work or solutions from this course given in previous years. Discussion of approaches to solving the homework problems after attempting to work the problems independently, however, is permitted and encouraged.
It is expected that during a test or examination, a student will not:
Following a test or examination, a student will not try to deceive teachers or graders by misrepresenting or altering his or her previous work. In advance of a test or exam, a student will not knowingly obtain access to the exam questions.
Departures from the above standards are contrary to fundamental principles of MIT and of the larger scientific community. Such departures are considered serious offenses for which disciplinary penalties, including suspension and expulsion, can be imposed.
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Chemistry of biomolecules i