Experimental Pathology

Courses

PATH 620a, Laboratory Rotations in Experimental Pathology  Staff

Laboratory rotations for first-year graduate students.
HTBA

PATH 622b, Laboratory Rotations in Experimental Pathology  Themis Kyriakides

Laboratory rotations for first-year graduate students.
HTBA

PATH 640a / B&BS 640a, Developing and Writing a Scientific Research Proposal  Katarina Politi

The course covers the intricacies of scientific writing and guides students in the development of a scientific research proposal on the topic of their research. All elements of an NIH fellowship application are covered, and eligible students submit their applications for funding. Enrollment limited to twelve. Required of second-year graduate students in Experimental Pathology. Registration allowed by prior authorization from course directors only.
M 9am-11am

PATH 650b, Cellular and Molecular Biology of Cancer  David Stern

A comprehensive survey of cancer research from the cellular to the clinical level. The relation of cancer to intracellular and intercellular regulation of cell proliferation is emphasized, as are animal models for cancer research. Background in molecular genetics and cell biology is assumed. Open to advanced undergraduates with permission of the organizers.
MWF 1pm-2pm

PATH 660b / C&MP 650b / PHAR 580b, The Responsible Conduct of Research  Barbara Ehrlich

Organized to foster discussion, the course is taught by faculty in the Pharmacology, Pathology, and Physiology departments and two or three senior graduate students. Each session is based on case studies from primary literature, reviews, and two texts: Francis Macrina's Scientific Integrity and Kathy Barker's At the Bench. Each week, students are required to submit a reaction paper discussing the reading assignment. Students take turns leading the class discussion; a final short paper on a hot topic in bioethics is required.
Th 11am-12:15pm

PATH 670b, Biological Mechanisms of Reaction to Injury  S. David Hudnall, Jon Morrow, Anita Huttner, Jeffrey Sklar, and Gilbert Moeckel

An introduction to human biology and disease as a manifestation of reaction to injury. Topics include organ structure and function, cell injury, circulatory and inflammatory responses, disordered physiology, and neoplasia.
TTh 11:35am-12:50pm

PATH 680a or b / C&MP 630a or b / PHAR 502a or b, Seminar in Molecular Medicine, Pharmacology, and Physiology  Staff

Readings and discussion on a diverse range of current topics in molecular medicine, pharmacology, and physiology. The class emphasizes analysis of primary research literature and development of presentation and writing skills. Contemporary articles are assigned on a related topic every week, and a student leads discussions with input from faculty who are experts in the topic area. The overall goal is to cover a specific topic of medical relevance (e.g., cancer, neurodegeneration) from the perspective of three primary disciplines (i.e., physiology: normal function; pathology: abnormal function; and pharmacology: intervention).
HTBA

PATH 681a / B&BS 681a, Advanced Topics in Cancer Biology  Ryan Jensen

This advanced course focuses on readings and discussion on three or four major topics in cancer biology, such as targeted therapy, tumor immunology, tumor metabolism, and genomic evolution of cancer. For each topic, the class starts with an interactive lecture, followed by critical analysis of primary research literature. Recent research articles are assigned, and a student leads discussions with input from faculty who are experts in the topic area. Prerequisite: PATH 650 or permission of the instructor. Open to all Ph.D., M.D./Ph.D., and M.P.H. students and to advanced undergraduates at the discretion of the instructor.
F 2pm-4pm

PATH 690a, Molecular Mechanisms of Disease  Narendra Wajapeyee

This course covers aspects of the fundamental molecular and cellular mechanisms underlying various human diseases. Many of the disorders discussed represent major forms of infectious, degenerative, vascular, neoplastic, and inflammatory disease. Additionally, certain rarer diseases that illustrate good models for investigation and/or application of basic biologic principles are covered in the course. The objective is to highlight advances in experimental and molecular medicine as they relate to understanding the pathogenesis of disease and the formulation of therapies.
TTh 2pm-3:30pm