Functional magnetic resonance imaging: data acquisition and analysis

Lectures: 2 sessions / week, 1 hour / session

Labs: 1 session / week, 1.5 hours / session

Discussions: 1 session / week, 1 hour / session

The course employs twice-weekly lectures and weekly laboratory and discussion sessions.

Laboratory includes fMRI data acquisition sessions and data analysis workshops. Assignments include reading of both textbook chapters and primary literature as well as fMRI data analysis in the laboratory. For each of the Discussion sections with an assigned article to read, students should post two questions to the class discussion forum at least 24 hours in advance.

Probability, linear algebra, differential equations, and introductory or college-level subjects in neurobiology, physiology, and physics are required.

Huettel, S. A., A. W. Song, and G. McCarthy. Functional Magnetic Resonance Imaging. 1st edition. Sunderland, MA: Sinauer Associates, Inc., 2004. ISBN: 9780878932887.

Note: The 2nd edition of this book was published after the Fall 2008 term, and Dr. Gollub recommends its use. Huettel, S. A., A. W. Song, and G. McCarthy. Functional Magnetic Resonance Imaging. 2nd ed. Sunderland, MA: Sinauer Associates, Inc., 2009. ISBN: 9780878932863.

This book will be supplemented by readings in the research literature and other books.

Problem sets are due one week after end of module. Lab reports are due one week after the analysis lab session.

Grades will be reduced by 10% per day until 1 week after due date, after which no assignments will be accepted.

Introduction to the course (Gollub)

Introduction to fMRI (Rosen)

MRI safety training

Lab 1: introduction to fMRI data and analysis (Bolar)

Problem set 2 due

Problem set 3 out

Quantitative perfusion and diffusion imaging biomarkers (Sorensen)

Physics of diffusion weighted imaging (Yendiki)

Stats 6: exploratory analysis, PCA, ICA, fuzzy clustering (Vangel)

Stats 7: causality (Vangel)

Quantitative neuroimaging biomarkers (Helmer)

Surface-based anatomical analysis (Salat)

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