Principles of pharmacology
Master
In Maynard (USA)
Description
-
Type
Master
-
Location
Maynard (USA)
-
Start date
Different dates available
The object of the course is to teach students an approach to the study of pharmacologic agents. It is not intended to be a review of the pharmacopoeia. The focus is on the basic principles of biophysics, biochemistry and physiology, as related to the mechanisms of drug action, biodistribution and metabolism. The course consists of lectures and student-led case discussions. Topics covered include: mechanisms of drug action, dose-response relations, pharmacokinetics, drug delivery systems, drug metabolism, toxicity of pharmacological agents, drug interaction and substance abuse. Selected agents and classes of agents are examined in detail.
Facilities
Location
Start date
Start date
Reviews
Subjects
- Physiology
- Biophysics
- Biochemistry
- Pharmacology
Course programme
Lectures: 3 sessions / week, 3 hours / session
The course material will focus on the basic principles of biophysics, biochemistry and physiology related to drug action and interaction, distribution, metabolism and toxicity. The course will consist of lectures, a clinical demonstration session at Massachusetts General Hospital, and lecturer and student-led case discussions.
Students must complete three assignments in this class: a case discussion, a drug evaluation report, and a problem set.
Most class sessions finish with a pair of student-led case discussions. These discussions cover some important topics in pharmacology which are either not addressed or dealt with only briefly in faculty lectures. Each case discussion will be analyzed by 2 students, and each student will be expected to give an oral presentation for about 10 minutes. These presentations may be used to satisfy part of the HST communication requirement
The drug evaluation report is a short paper dealing with a relatively new FDA-approved drug selected from a list provided by the instructors.
Students will take a midterm and final exam.
HST students taking this course will be graded on an Excellent, Satisfactory, Unsatisfactory basis. The grade of Marginally Satisfactory may also be given in borderline cases. HST (or HMS) M.D. student grades will be recoded as Pass/Fail. Student evaluations will be based on written homework, classroom work and oral presentations, as well as the midterm and final examinations.
Golan, D., et. al., eds. Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. Philadelphia, PA: Lippincott Williams and Wilkins, 2004. ISBN: 9780781746786.
Hardman, J. G., et. al., eds. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 10th ed. New York, NY: McGraw-Hill, 2001. ISBN: 9780071354691.
This work, known as "G and G" (for the original editors, Goodman and Gilman), is an excellent reference many of you will want on your shelves. New editions have been coming out at roughly five year intervals.
Don't show me this again
This is one of over 2,200 courses on OCW. Find materials for this course in the pages linked along the left.
MIT OpenCourseWare is a free & open publication of material from thousands of MIT courses, covering the entire MIT curriculum.
No enrollment or registration. Freely browse and use OCW materials at your own pace. There's no signup, and no start or end dates.
Knowledge is your reward. Use OCW to guide your own life-long learning, or to teach others. We don't offer credit or certification for using OCW.
Made for sharing. Download files for later. Send to friends and colleagues. Modify, remix, and reuse (just remember to cite OCW as the source.)
Learn more at Get Started with MIT OpenCourseWare
Principles of pharmacology