Tales from the Genome - 23andMe

Lesson 1: Introduction to traits and heredity

Trait variation and categorization, basic models of inheritance, and the connection via DNA. Check out theconcept map for this lesson.

Lesson 2: Defining the genome

DNA structure, chromosomes, and genome organization. Check out the concept map for this lesson.

Lesson 3: How a genome works

Protein coding genes, transcription, translation, discerning the genetic code, and alleles. Check out theconcept map for this lesson.

Lesson 4: Gene regulation

Non-coding DNA, regulatory regions of genes, and transcription factors. Check out the concept map for this lesson.

Lesson 5: Transmission of genes and traits

Family relationships and pedigrees, inheritance patterns, allele dominance, and chromosome dynamics. Check out the concept map for this lesson.

Lesson 6: Origin of mutation/variation

Types of mutations, various causes of mutation, allelic frequency, and the spread of alleles in a population. Check out the concept map for this lesson.

Lesson 7: How to obtain and interpret personal genetic information

Personalized genetics: sample acquisition, DNA extraction and processing, and interpretation of results. Check out the concept map for this lesson.

Lesson 8: Simple genetic traits

Molecular causes of monogenic traits, loss-of-function vs. gain-of-function alleles, and dominance. Check out the concept map for this lesson.

Lesson 9: Multifactorial traits

Polygenic traits, complex traits with an environmental effect, qualitative and quantitative measures, twin studies, relative risk, and genome-wide association studies (GWAS). Check out the concept map for this lesson.

Lesson 10: Pharmacogenetics: genes and drugs

Pharmacokinetics and pharmacodynamics, alleles affecting drug metabolism, and personalized medicine. Check out the concept map for this lesson.

Lesson 11: Human ancestry and evolution

Identity by state (IBS), Identity by descent (IBD), relative finder, maternal and paternal lineages, neanderthal interbreeding, and human/chimp evolution. Check out the concept map for this lesson.

Lesson 12: The immortal genome (putting genetics to work)

Personal decisions, legal questions, professional options, and the future of genetics. Check out the concept map for this lesson.

Bonus Lesson: Discovering DNA in your Kitchen

Using only normal household items, even YOU can extract DNA and see it live and in person. At the end of this lesson you'll have the best new party trick EVER. (just remember to bring strawberries) Here is the protocol/procedure to make it happen.