Translational Cancer Medicine MRes

Course detail Description

The Translational Cancer Medicine MRes study pathway offers unique opportunities for you to join experienced research teams and work on particular projects from the outset. This course will allow you to develop an in-depth understanding of research methods, and of how theoretical academic studies and skills relate to research projects.

You will explore Fundamentals of Translational Cancer Medicine, in both laboratory projects and lectures, providing you with advanced knowledge and skills to conceptualise, design, conduct and critically appraise specialist research.

Examples of research project titles could include:

Discipline

Supervisor

Project title

Epidemiology

Dr Mieke Van Hemelrijck

Serum biomarkers in relation to risk and progression of cancer – an analysis using the Swedish Apolipoprotein MORtality RISk study (AMORIS

Cancer functional genomics, computational biology

Dr Francesca Ciccarelli

Validation of actionable genes in colorectal cancer

Cancer Bioinformatics

Dr Anita Grigoriadis & Dr Cheryl Gillett

Characterisation of different immune cells in lymph nodes

Cancer Cell Biology

Dr James Arnold

Tumour associated macrophages in cancer progression

Cancer Cell Biology

Dr Jeremy Carlton

Regulation of cell division and receptor degradation by the ESCRT-machinery

Cancer Cell Biology

Dr Gilbert Fruhwirth

Multi-modal in vivo imaging for monitoring cancer treatment

Imaging

Prof Vicky Goh &
Prof Gary Cook

Optimising multimodality treatment response assessment with imaging

Leuukemia Biology

Prof Eric So

Studying of cancer cell heterogeneity in human AML

Cancer Head/Neck

Prof Mahvash Tavassoli

Predictive Biomarkers of Treatment Resistance in Head and Neck Squamous Cell Carcinoma

Molecular Pathology

Prof Sarah Pinder Molecular pathology of breast cancer precursors

Haemato-oncology

Prof Farzin Farzaneh & Dr Kiki Ioannou

High throughput analysis of modulators of cellular immunity against cancer associated antigens

Haemato-oncology

Dr Alan Ramsay

Investigating the tumour microenvironment (TME) and immune suppression in lymphoma

Haemato-oncology

Prof Francesco Dazzi

Tumour associated stroma and therapeutic targets

Haemato-oncology

Prof Ghulam Mufti

Truncal vs branch mutations in MDS/AML

Haemato-oncology

Prof Ghulam Mufti

Immune response in aplastic anaemia

Tumour Immunology

Prof Joy Burchell

Changes in post-translational modifications (O-linked glycosylation) of breast cancer: The effect on tumour behaviour and immune recognition

Tumour Immunology

Prof Tony Ng

Investigations of the impact of EGFR/HER3 treatments on the cancer: immune stromal microenvironment interface – via RNA-binding protein FUS

Clinical Tumour Immunology

Dr Debashis Sarker &
Dr James Spicer

Factors affecting patient recruitment and experience in Phase 1 trials

Tumour Immunology

Dr John Maher

Genetic targeting of T-cells against cancer

Stem Cells and Bone Cancer

Prof Agamemnon Grigoriadis

Mechanisms of bone tumour growth and metastasis

Cancer Cell Biology

Dr Claire Wells

Exploring the fesability of using nucleolin as a drug target

Cancer Studies

Dr Shahram Kordasti

The role of CD95+ Tregs in controlling autoimmunity

Cancer Immunology

Dr Sophie Papa

Targeting SF-25 with CAR T-cells

Breast Cancer Imagaing

Prof Arnie Purushotham

FORCE/Tissue Stresses of Cance

Further literature

Course format and assessment

Teaching

We use lectures, seminars and group meetings to deliver most of the modules on the course.

You will gain hands on research experience in two six-month lab projects. On average teaching consists of:

• 40 hours of lectures
• 1.5 – 3 hours per week of Lab/group meetings (depending on projects)
• supervision/feedback during each lab roation

You will also be expected to undertake a significant amount of independent study.

Typically, 1 credit equates to ten hours of work.

Throughout the year, you will also attend literature reviews and journal clubs that the labs/departments organise, as well as any other internal or external seminars deemed relevant to your projects/assignments.

Assessment

The primary method of assessment for this course is a combination of written essays, a thesis (research report), a presentation/Q&A session regarding the research report and a draft of a scientific paper.

The study time and assessment methods detailed above are typical and give you a good indication of what to expect. However, they are subject to change.

Extra information

Occupational health clearance will be required for some of the projects.

Read more

Structure

Year 1 Courses are divided into modules. You will normally take modules totalling 180 credits. Required Modules

You are required to take:

• Fundamentals of Translational Cancer Medicine (30 credits)

• Laboratory Based Research Project 1 (75 credits)

• Laboratory Based Research Project 2 (75 credits)

King’s College London reviews the modules offered on a regular basis to provide up-to-date, innovative and relevant programmes of study. Therefore, modules offered may change. We suggest you keep an eye on the course finder on our website for updates: Optional Modules