Undergraduate certificate Engineering Biology

CBE 228 Energy Technologies in the 21st Century (See MAE 228)

CBE 245 Introduction to Chemical and Biochemical Engineering Principles Fall STN Application of the principles of conservation of mass and energy to the design and analysis of chemical processes. Elementary treatment of single and multiphase systems. First law of thermodynamics for closed and open systems. Steady state and transient analysis of reacting and nonreacting systems. Three lectures, one preceptorial. Prerequisite: CHM 201. M. Brynildsen

CBE 246 Thermodynamics Spring STN Basic concepts governing the equilibrium behavior of macroscopic fluid and solid systems of interest in modern chemical engineering. Applications of the first law (energy conservation) and second law (temperature, entropy, reversibility) to open and closed systems. Thermodynamic properties of pure substances and mixtures. Phase equilibrium and introduction to reaction equilibrium. Introduction to the molecular basis of thermodynamics. Applications include thermodynamics of protein stability, the Earth's energy balance, energy conversion schemes, and the binding of ligands to proteins. Prerequisites: CBE 245 and MAT 201. R. Register

CBE 250 Separations in Chemical Engineering and Biotechnology Fall STN Fundamental thermodynamic principles and transport processes that govern separations in biotechnology and chemical processing. Staged operations, such as distillation and chromatography, are developed based on coupling phase equilibrium with mass balances. Transport processes driven by electric fields, centrifugal fields, or hydrodynamics provide the basis for understanding ultracentrifugation, membrane process, and electrophoresis. Three lectures. Prerequisites: CBE 245 and CBE 246. MAE 305 and CHM 301 may be taken concurrently. N. Lape

CBE 260 Ethics and Technology: Engineering in the Real World (also

EGR 260

CBE 305 Mathematics in Engineering I (See MAE 305)

CBE 318 Fundamentals of Biofuels (See ENE 318)

CBE 335 The Energy Water Nexus (also

MAE 338

CBE 341 Mass, Momentum, and Energy Transport Fall STN Survey of modeling and solution methods for the transport of fluids, heat, and chemical species in response to differences in pressure, temperature, and concentration. Steady state and transient behavior will be examined. Topics include fluid statics; conservation equations for mass, momentum and energy; dimensional analysis; viscous flow at high and low Reynolds number; thermal conduction; convective heat and mass transfer, correlations; diffusion and interphase mass transfer. Working knowledge of calculus, linear algebra and ordinary differential equations is assumed. Prerequisites: CBE 245, CBE 246 & MAE 305. Can take MAE 305 concurrently. P. Brun

CBE 342 Fluid Mechanics Not offered this year Elements of fluid mechanics relevant to simple and complex fluids. Topics include macroscopic balances; derivation of differential balance equations and applications to unidirectional flows; treatment of nearly unidirectional flows through the lubrication approximation; introduction to turbulent flow; flow through porous media; capillary flows; dispersed two-phase flows; and hydrodynamic stability. Three lectures. Prerequisite: CBE 341. S. Sundaresan

CBE 346 Chemical Engineering Laboratory Spring STL An intensive hands-on practice of engineering. Experimental work in the areas of separations, heat transfer, fluid mechanics, process dynamics and control, materials processing and characterization, chemical reactors. Development of written and oral technical communication skills. One lecture, two three-hour laboratories. Prerequisites: CBE 246 and CBE 341 or equivalents. S. Sundaresan, J. Nunes, L. Loo

CBE 351 Junior Independent Work Fall Subjects chosen by the student with the approval of the faculty for independent study. A written report, examination, or other evidence of accomplishment will be required. A. Link

CBE 352 Junior Independent Work Spring Subjects chosen by the student with the approval of the faculty for independent study. A written report, examination, or other evidence of accomplishment will be required. A. Link

CBE 415 Polymers (also

CHM 415

CBE 419 Enzymes Spring STN Enzymes are the engines that fuel life, catalyzing a vast array of different chemical reactions. This course will focus first on enzyme kinetics and the structural biology of enzymes. With these tools we will next move to a series of case studies about different enzymes and enzyme families. A. Link

CBE 421 Catalytic Chemistry (also

CHM 421

CBE 422 Molecular Modeling Methods Spring STN This course offers an introduction to computational chem¬istry and molecular simulation methods. Computational chemistry involves using quantum mechanical models to obtain the electronic structure of atoms and molecules. Monte Carlo and Molecular Dynamics methods use input from quantum chemistry and empirical potentials to obtain equilibrium and non-equilibrium properties of fluids and materials. As computer power continues its exponential growth, these methods find increasing applications in engineering, chemistry, physics and biology. A. Panagiotopoulos

CBE 425 Polymer Rheology Fall A systematic development of the principles and applications of the science of rheology with an emphasis on the development of stress-velocity constitutive equations. Vector and tensor mathematics and Newtonian fluid dynamics are reviewed. Develops the physical and mathematical nature of stress and deformations in materials. Covers the use of theory and application of rheological equations of state. F. Morrison

CBE 427 Environmental Biotechnology Spring STN This course will study aspects of the top 25 environmental disasters that lend themselves to analysis by application of fundamental principles from mass, momentum and heat transfer. Some examples include: dissolution from a pipe wall associated with lead contamination of the municipal water supply in Flint, MI, transport of polychlorinated biphenyl (PCB) contamination into the sediments of the Hudson River, biodegradation of oil droplets created by the addition of surfactant following the Deepwater Horizon explosion, oxygen depletion in the Gulf of Mexico Dead Zone, and spread of methylisocyanate gas from the Union Carbide plant in Bhopal. R. Ford

CBE 432 The Cell as a Chemical Reactor Not offered this year Presents a framework for the analysis of cellular responses, such as proliferation, migration, and differentiation. Emphasis on mechanistic models of biotransformation, signal transduction, and cell-cell communication in tissues. Focuses first on unit operations of cell physiology transcription, translation, and signal transduction. Models of these processes will rely on tools of reaction engineering and transport. Process dynamics and control will then be used to analyze the regulatory structure of networks of interacting genes and proteins. Prerequisites: MOL 214 and MAE 305 or their equivalents. S. Shvartsman

CBE 433 Introduction to the Mechanics and Dynamics of Soft Living Matter (also

MSE 424

CBE 434 Biotechnology (See MOL 433)

CBE 438 Biomolecular Engineering (also

MOL 438

CBE 439 Quantitative Physiology & Tissue Design Fall A treatment of the quantitative tools to understand the human body. Course reviews cell biology and anatomy, then examines cells, tissues, and organs using principles from engineering kinetics and transport processes. Topics include: cell physiology; organ system physiology (including the cardiovascular, renal, and respiratory systems); and pathophysiology. Clinical treatments for human disease will also be analyzed. C. Nelson

CBE 440 The Physical Basis of Human Disease (also

GHP 450

CBE 441 Chemical Reaction Engineering Spring STN Stoichiometry and mechanisms of chemical reaction rates, both homogeneous and catalytic; adsorption, batch, continuous flow, and staged reactors; coupling between chemical reaction rates and mass, momentum, and energy transport; stability; optimization of reactor design. Application to environmental and industrial problems. Two lectures, one preceptorial. Prerequisites: CBE 246 and CBE 341. J. Avalos

CBE 442 Design, Synthesis, and Optimization of Chemical Processes Fall STL Introduction to chemical process flow-sheeting; process design, sizing and cost estimation of total processes; process economics; introduction to optimization, linear programming, integer programming, and nonlinear programming; heat integration methods, minimum utility cost, minimum number of units, network optimization. Two lectures, one laboratory. Prerequisites: CBE 341, CBE 346, and CBE 441. A. Panagiotopoulos, C. Smith

CBE 445 Process Control Not offered this year A quantitative study of the principles of process dynamics and control. Dynamic behavior of chemical process elements; analysis and synthesis of linear feedback control systems with special emphasis on frequency response techniques and scalar systems. Two lectures. Prerequisite: MAE 305, which may be taken concurrently. S. Sundaresan

CBE 447 Metabolic Engineering (also

GHP 457

CBE 451 Senior Independent Work Fall A one semester study of an important problem or topic in chemical and biological engineering. Projects may be experimental, computational, or theoretical. Topics selected by the students from suggestions by the faculty. Written report required. A. Link

CBE 452 Senior Independent Work Spring A one semester study of an important problem or topic in chemical and biological engineering. Projects may be experimental, computational, or theoretical. Topics selected by the students from suggestions by the faculty. Written report required. A. Link

CBE 454 Senior Thesis Spring A full year study of an important problem or topic in chemical and biological engineering culminating in a senior thesis. Projects may be experimental, computational, or theoretical. Topics selected by the students from suggestions by the faculty. Written thesis, poster presentation, and oral defense required. The senior thesis is recorded as a double course in the spring. Departmental permission required. A. Link

CBE 454R Senior Thesis-Resubmission Spring An experimental, computational, and theoretical study of an important problem or topic in chemical engineering. Topics selected by the students from suggestions by the faculty. Written thesis and oral defense required. The senior thesis is equivalent to a yearlong study and is recorded as a double course in the spring. J. Benziger