Biological & Biomedical Sciences

Courses

B&BS 501b, Responsible Conduct of Research  Barbara Kazmierczak and John Forrest

The course is held in six (6) 1.5 hour sessions, with the participation of Yale faculty members. The course format is lecture with group discussion and case studies.  0 Course cr
HTBA

B&BS 503b, RCR Refresher for Senior BBS Students  Anthony Koleske and John Alvaro

This course meets the NIH requirement that students receive training in the responsible conduct of research at least every four years. The course has two components: (1) one large-group session is held for all fourth-year BBS students; the main topics are scientific misconduct and authorship; and (2) each Ph.D. program will subsequently host one or two additional sessions just for fourth-year students in its program. Attendance is taken, and students who attend both components of the course receive a grade of Satisfactory. The course is graded Satisfactory/Unsatisfactory.
HTBA

B&BS 550b, SkillDvlpmtDvrsScntfcCareers  Susan Baserga, Anthony Koleske, and Barbara Kazmierczak

 0 Course cr
HTBA

B&BS 640a / PATH 640a, Developing and Writing a Scientific Research Proposal  Katarina Politi

The course covers the intricacies of scientific writing and guides students in the development of a scientific research proposal on the topic of their research. All elements of an NIH fellowship application are covered, and eligible students submit their applications for funding. Enrollment limited to twelve. Required of second-year graduate students in Experimental Pathology. Registration allowed by prior authorization from course directors only.
M 9am-11am

B&BS 680b / IMED 680b, Topics in Human Investigation  Joseph Craft

The course teaches students about the process through which novel therapeutics are designed, clinically tested, and approved for human use. It is divided into two main components, with the first devoted to moving a chemical agent from the bench to the clinic, and the second to outlining the objectives and methods of conducting clinical trials according to the FDA approval process. The first component describes aspects of structure-based drug design and offers insight into how the drug discovery process is conducted in the pharmaceutical industry. The format includes background lectures with discussions, labs, and computer tutorials. The background lectures include a historical perspective on drug discovery, the current paradigm, and important considerations for future success. The second component of the course provides students with knowledge of the basic tools of clinical investigation and how new drugs are tested in humans. A series of lectures and discussions provides an overview of the objectives, research strategies, and methods of conducting patient-oriented research, with a focus on design of trials to test therapeutics. Each student is required to participate (as an observer) in an HIC review, in addition to active participation in class. Consent of instructor required.
Th 3pm-4:30pm

B&BS 681a / PATH 681a, Advanced Topics in Cancer Biology  Ryan Jensen

This advanced course focuses on readings and discussion on three or four major topics in cancer biology, such as targeted therapy, tumor immunology, tumor metabolism, and genomic evolution of cancer. For each topic, the class starts with an interactive lecture, followed by critical analysis of primary research literature. Recent research articles are assigned, and a student leads discussions with input from faculty who are experts in the topic area. Prerequisite: PATH 650 or permission of the instructor. Open to all Ph.D., M.D./Ph.D., and M.P.H. students and to advanced undergraduates at the discretion of the instructor.
F 2pm-4pm

B&BS 879a, Theory and Practice of Scientific Teaching  Elizabeth Luoma

W 9am-11am