Health Degrees in Dundee City

...so that accumulation of unfolded, misfolded, or damaged proteins can be cleared before they become deleterious. We recently reported that proteasomal degradation... Learn about: Human Diseases...

...in the field as pre-clinical validation models. Minimising use (by reduce and replace practices) however is an ethical imperative. To date, adequately... Learn about: Medical training, Virtual CAD, 3d training...

...the occurrence of which is associated with acute cognitive dysfunction, confusion, coma, seizures, cardiac arrhythmias and rarely, death. Repeated episodes... Learn about: Diabetes Care, Diabetes Clinical Care, Health Care...

...time between diagnosis and treatment is still an unmet clinical need. Optical endoscopy and associated biophotonics imaging and sensing techniques do... Learn about: Clinical routine...

...within the NHS (3). However, little work has been done to look at how this manifests in undergraduate medical education in the UK. This PhD work will focus... Learn about: Clinical Governance, Clinical Teaching, Clinical Issues...

...the impracticality of seeking consent of patients, challenges of de-identification of image data, absence of non-proprietary software for efficient handling... Learn about: Data Management, Research data, Medical training...

...catalogue of genetic abnormalities in human cancer, and in some tumour types provided classifications useful for clinical decision making. However... Learn about: Clinical phenotype, Genetic abnormalities, Clinical decision...

...to comprehensively classify the GSK3 regulated proteome in metabolic tissues. However, the majority of the known targets control cell proliferation... Learn about: Human CLL, Chronic lymphocytic...

...show that cardiac insulin resistance may be associated with increased deposition of ECM components, such as collagen III and collagen IV. Importantly...

...The principal outcome of the series of studies proposed in this PhD will be to establish that IAH develops through the process of habituation... Learn about: Diabetes Care, Diabetes Clinical Care, Severe hypoglycaemia...

...invasive and not without risk. Despite this, year-on-year, ART is increasingly utilized worldwide. There is clearly an unmet need for the development... Learn about: Phenotypic Screening, Drug Discovery...

...make high-impact findings relevant to clinical practice,through cross-validation of clinical and cell/molecular insights. To follow up the preliminary...

...effects of metformin are exerted irrespective of diabetes status[1, 2], through poorly understood ‘immunometabolic’ mechanisms that are different from... Learn about: Human Disease, IT risk...

...whilst these is no monitoring between intervening patient visits. We have previously shown that speech can be used to replicate the Unified Parkinson’s... Learn about: Physical computing, Physical Education, Physical Intervention...

...its molecular pathogenesis and provide new precision medicine strategies for diagnosis, prevention and treatment including novel NRF2 inhibitors as... Learn about: Human solid...

...New technologies such as NanoString and Ion Torrent allow immune-based transcriptomes to be produced rapidly and reliably from formalin-fixed... Learn about: IT risk...

...LRRK2 mutation carriers will develop PD. This project will investigate whether two new diagnostic approaches can predict those LRRK2 mutation carriers...

...phenethyl isothiocyanate and bis(2-hydroxybenzylidene)acetone, inhibit mTOR. The aim of this project is to gain insights into the mechanism by which sulfhydryl-reactive...

...the sensitivity of mice to hepatic steatosis and NASH [2]. As anticipated, we found the Nrf2-null animals exhibited decreased expression of antioxidant genes...

...has recently published an exemplar GWAS paper on headache using the UK Biobank cohort and other analyses are ongoing, including meta-analyses with related cohorts...