Health Degrees in the Scotland

...build on our exciting, unpublished findings that these DUBs are novel regulators of protein homeostasis. In this PhD project, you will use innovative genetic... Learn about: Structural Biology, Biology Science...

...proteasome homeostasis is regulated in cells, and to use these tools to identify new regulators and drugs modulating proteasomal degradation... Learn about: Human Diseases...

...replace these models is currently available and secondly because they both constitute vitally important pre-clinical evidence with published acceptance... Learn about: Medical imaging, 3d training, Physical prototype...

...to learn in vivo techniques required to assess cardiac function (cardiac pressure-volume (PV) loop analysis, and vascular function by laser Doppler)... Learn about: Diabetes Clinical Care, Health Care, Blood glucose...

...to surgical resection or radiation therapy of benign and malignant tumors... Learn about: Clinical routine...

...on the UK undergraduate medical education context and explore how this in included in curricula from the viewpoints of different stakeholders... Learn about: Developing Clinical, Clinical coding, Clinical Service...

...utilized for multiple research projects at once without having to create multiple copies Speed and Scaling: methods to optimise the speed of processing... Learn about: Medical training, Data Management, Research data...

...potential translational impact as targets e.g. repurposing of existing targets and agents to application in oesophageal cancer precision medicine strategies... Learn about: Clinical phenotype, Genetic abnormalities, Clinical decision...

...We also have access to the most commonly used AML cell lines and primary human material for validation studies. Normal controls for comparative studies... Learn about: Human CLL, Chronic lymphocytic...

...of the ECM in cardiac insulin resistance and CHF and ECM may well become a target for therapy in diabetic cardiovascular disease. This research project...

...to working at the interface between human and bench translational research... Learn about: Diabetes Care, Severe hypoglycaemia, Diabetes Nutrition...

...We will use this preliminary data to present to both industrial and non-industrial funding sources to facilitate translation of these potential compounds to the clinic... Learn about: Phenotypic Screening, Drug Discovery...

...they will be supervised by Dr Rena. All methodologies are established either by the supervisors or available through established collaborations[2...

...relevance to human disease,it is desirable to extend our studies from rodent-derived cells to include human-derived cells. To do this, the student... Learn about: Human Disease, IT risk...

...Accurate quantification of Parkinson’s Disease (PD) symptom severity is critical to assist neurologists optimize treatment and mitigate PD symptoms... Learn about: Physical Chemistry, Clinical PhD, Physical Education...

...and integrated proteogenomic analyses to further characterise this classic subtype in SCCs across multiple anatomical sites. This proposal will investigate... Learn about: Human solid...

...have changed the therapeutic landscape for many cancers, but the strong association between immunosuppression/immune evasion and poor SCC outcomes implies... Learn about: IT risk...

...and blood and CSF (Prof Eduardo Tolosa, Barcelona and Dundee). How is the project collaborative? This project is collaborative as the student will...

...The project will involve cell culture, transfection, quantitative real-time PCR, immunoblotting, and immunofluorescence imaging...

...of the transcription factor, and also siRNA knockdown of Nrf2. Key measures in the models will be oxidative balance of the cell in response to the...