Health Degrees in the Scotland

...rather than considering these as separate areas to be investigated in isolation. Abnormalities in these pathways cause numerous diseases including cancer... Learn about: DNA Replication, DNA repair...

...This process relies on modification of proteins with ubiquitin, a signal to target destruction of modified proteins. Ubiquitylation is a very dynamic process... Learn about: Structural Biology, Biology Science...

...such as cancer and neurodegenerative disorders. Our interest is to understand how the activity of the ubiquitin-proteasome system is regulated in cells... Learn about: Human Diseases...

...to create more complex physical phantoms of the human abdomen containing soft tissues, hard tissues, organs and the rib cage. Hard and soft polymers... Learn about: Physical prototype, Virtual CAD, 3d training...

...Repeated episodes of hypoglycaemia have also been associated with significant end-organ disease, particularly in the heart and brain and are of major concern... Learn about: Diabetes Clinical Care, Diabetes Nutrition, Blood glucose...

...The proposed work aims to design and develop MRI compatible biophotonic probes for endoscopic microscopy (endomicroscopy) and spectroscopy for in... Learn about: Clinical routine...

...be based on experiential approaches to learning is gaining ground. However, there is both little discussion in the literature on what form experiential... Learn about: Clinical coding, Developing Clinical, Clinical Issues...

...and existing software suit, the Research Data Management Platform (RDMP) software. Challenges include Storage: methods to ensure the same image can... Learn about: Research data, Data Management, Medical training...

...This approach has provided functional insights that had not been possible with genomic studies alone, and in doing so suggested key disease drivers... Learn about: Clinical phenotype, Genetic abnormalities, Clinical decision...

...the feasibility of developing novel interventions. Methodology: We have cryopreserved CLL cells, plus isolated DNA, RNA and protein. We also have access... Learn about: Human CLL, Chronic lymphocytic...

...show that cardiac insulin resistance may be associated with increased deposition of ECM components, such as collagen III and collagen IV. Importantly...

...The principal outcome of the series of studies proposed in this PhD will be to establish that IAH develops through the process of habituation... Learn about: Severe hypoglycaemia, Diabetes Care, Diabetes Clinical Care...

...The project will be an unrivalled opportunity for a student to learn a raft of advance biological techniques as well as gain hands-on experience with industry-standard... Learn about: Phenotypic Screening, Drug Discovery...

...as well as changes in prescription of oral anti-hyperglycaemic medications or insulin. This element will comprise one third of the studentship...

...translational cross-validation of clinical observations with cell/molecular findings,as demonstrated in our highly interdisciplinary recent work... Learn about: Human Disease, IT risk...

...Ultimately, this may lead to a fragmented picture of daily aspects in understanding the extent of PD symptoms, which leads to suboptimal treatment... Learn about: Physical Intervention, Physical computing, Clinical PhD...

...its molecular pathogenesis and provide new precision medicine strategies for diagnosis, prevention and treatment including novel NRF2 inhibitors as... Learn about: Human solid...

...SCC using machine learning algorithms (decision tree building and linear discriminant analysis). We propose to develop, optimize and validate this approach... Learn about: IT risk...

...The PhD project will be based in either Dundee or Edinburgh, but will be highly collaborative with significant interaction with the co-supervisor at the partner University...

...phenethyl isothiocyanate and bis(2-hydroxybenzylidene)acetone, inhibit mTOR. The aim of this project is to gain insights into the mechanism by which sulfhydryl-reactive...