Health Degrees in the Scotland

...phosphorylation and ubiquitin networks control a variety of cellular processes including autophagy, DNA repair, DNA replication, mitochondrial quality control... Learn about: DNA Replication, DNA repair...

...and ubiquitin signals are removed/edited by deubiquitinating enzymes (DUBs). Failure to eliminate damaged/misfolded proteins is an underlying cause... Learn about: Biology Science, Structural Biology...

...A range of other projects from MRC PPU scientists are advertised on this website. Rotations provide valuable experience and help with deciding on the choice... Learn about: Human Diseases...

...properties comparable to real tissue will be... Learn about: Physical prototype, Medical imaging, Medical training...

...on cardiovascular function in rodent models of type 2 diabetes or controls. The candidate will examine for tissue markers of oxidative stress and inflammation... Learn about: Blood glucose, Diabetes Clinical Care, Diabetes Nutrition...

...This multimodality imaging would be used for control of image guided interventions such as MRgFUS. Magnetic Resonance Imaging (MRI) guided diagnostic biopsy... Learn about: Clinical routine...

...within the NHS (3). However, little work has been done to look at how this manifests in undergraduate medical education in the UK. This PhD work will focus... Learn about: Clinical Statistics, Clinical coding, Developing Clinical...

...The medical digital images are routinely collected and archived by the NHS. Such images, especially when linked to other routinely collected health... Learn about: Data Management, Medical training, Research data...

...and how this affects the cancer cell phenotype and ultimately the clinical phenotype. In collaboration with the Scottish genomes partnership... Learn about: Clinical decision, Genetic abnormalities, Clinical phenotype...

...From this we can determine biological pathways (eg mitochondrial, metabolic etc) that associate with clinical outcomes, with a view to develop novel strategies... Learn about: Chronic lymphocytic, Human CLL...

...takes an interdisciplinary approach, which will be facilitated by Dr Kang’s expertise in in vivo insulin resistance physiology and Professor Lang...

...and so will be immediately translatable into clinical practice. There is the opportunity to learn in vivo techniques and to be part of a laboratory committed... Learn about: Diabetes Care, Diabetes Clinical Care, Diabetes Nutrition...

...(Martins da Silva et al., 2017). Couples instead rely on Artificial Reproduction Technology (ART), such as IVF and ICSI, which is expensive... Learn about: Phenotypic Screening, Drug Discovery...

...the student will use state-of-the-art national data hosted by the Scottish Diabetes Research Network epidemiology group. The additional power afforded...

...relevance to human disease,it is desirable to extend our studies from rodent-derived cells to include human-derived cells. To do this, the student... Learn about: IT risk, Human Disease...

...required to analyse the data (Thanasis). We aim to keep this process iterative as we plan to use this project as a baseline for a longer-term fruitful collaboration... Learn about: Physical computing, Physical Intervention, Clinical PhD...

...malignancies and are a major cause of cancer mortality. Genomic landscaping studies have identified a ’classic subtype’ of SCC, including lung... Learn about: Human solid...

...SCC using machine learning algorithms (decision tree building and linear discriminant analysis). We propose to develop, optimize and validate this approach... Learn about: IT risk...

...wherever possible. Additional Project Info This PhD project is part of a Dundee-Edinburgh Parkinson’s Research Initiative that brings together clinicians...

...sulfhydryl-reactive Nrf2 activators by using compounds of distinct chemical classes, and test for the potential requirement of Nrf2 for mTOR inhibition...