University of Dundee courses

...and existing software suit, the Research Data Management Platform (RDMP) software. Challenges include Storage: methods to ensure the same image can... Learn about: Research data, Data Management, Medical training...

...has found gene-specific DNA methylation to be associated with melanoma metastasis1. Development of a robust assay for NHS delivery is achievable... Learn about: NHS health, NHS Training...

...and how this affects the cancer cell phenotype and ultimately the clinical phenotype. In collaboration with the Scottish genomes partnership... Learn about: Clinical phenotype, Genetic abnormalities, Clinical decision...

...Recent studies (including our own unpublished results) have indicated a role for mitochondrial activity as a significant regulator of cellular bioenergetics in... Learn about: Chronic lymphocytic, Human CLL...

...a leading expert in cardiology and clinical pharmacology with an interest in pathophysiology of cardiac metabolic disease...

...and whether it is possible to reverse or prevent this process. This work will be carried out in parallel with clinical studies in people with type 1 diabetes... Learn about: Severe hypoglycaemia, Diabetes Nutrition, Diabetes Care...

...Infertility is a significant global problem affecting ~1 in 7, or ~80 million couples (Barratt et al., 2017). Although the causes of infertility are heterogeneous... Learn about: Drug Discovery, Phenotypic Screening...

...Method Patients will be recruited and clinically assessed by a band 5 research nurse employed part-time 1.5 days/week for 2 years to support the study... Learn about: Chemotherapy CIPN...

...The remainder will be an appraisal of acute effects of sulfasalazine on diabetic and haematological responses, mainly using cell models. This will include...

...relevance to human disease,it is desirable to extend our studies from rodent-derived cells to include human-derived cells. To do this, the student... Learn about: Human Disease, IT risk...

...because the dynamics of these “phosphorylation cycles” can control many critical features of a signal response 1. This PhD project will use the Xenopus... Learn about: Human cells, Cell Biology...

...Here we aim to use a range of model systems, including human induced pluripotent stem cell (iPSC) technologies, to mirror tau pathophysiology that occurs...

...we demonstrated Patient Reported Outcome Measures (PROMs) provide a reliable additional dimensionality in understanding daily symptom severity in mental disorders cohorts... Learn about: Physical Intervention, Physical Chemistry, Physical Education...

...Methodolology: We will perform studies on hepatic cell systems where ATM protein production has been enhanced or removed through genetic manipulation... Learn about: Nature Genetics...

...and integrated proteogenomic analyses to further characterise this classic subtype in SCCs across multiple anatomical sites. This proposal will investigate... Learn about: Human solid...

...of cancer mortality with limited therapeutic options for advanced disease. Immunotherapies such as immune checkpoint inhibitors (ICi) have changed... Learn about: IT risk...

...LRRK2 mutation carriers will develop PD. This project will investigate whether two new diagnostic approaches can predict those LRRK2 mutation carriers...

...programs of electrical stimulation can reverse insulin resistance and steato-hepatitis resolving NASH in patients. The project will measure a range...

...to combat the development of vemurafenib drug-resistance (1). We have also recently demonstrated that mutational inactivation of TGF receptors in skin...

...which have a characteristic chemical signature: the ability to react with sulfhydryl groups. Using the human osteosarcoma cell line U2OS, we recently found that two Nrf2 activators...