University of Dundee courses

...development of novel computer vision methods for biomarker extraction, validation of novel algorithms and machine learning approaches and discovery... Learn about: Data Management, Medical training, Research data...

...is crucial to avoid significant toxicities and unnecessary NHS health costs. Detecting high-risk patients likely to benefit is therefore a clinical priority... Learn about: NHS Training, NHS health...

...pathogenic mechanisms .In this project, disease mechanisms will be functionally validated using in vitro models with priority given to those with the highest... Learn about: Clinical decision, Genetic abnormalities, Clinical phenotype...

...Recent studies (including our own unpublished results) have indicated a role for mitochondrial activity as a significant regulator of cellular bioenergetics in... Learn about: Human CLL, Chronic lymphocytic...

...ECM-receptor signalling, and endothelial dysfunction in the heart with cardiac insulin sensitivity will provide important and novel insights into the...

...Confirmation of this will provide the first clear explanation as to why IAH develops in people with T1 and long-duration T2D who are exposed to multiple episodes of hypoglycaemia... Learn about: Diabetes Nutrition, Diabetes Clinical Care, Diabetes Care...

...The project will then focus on characterising in greater depth the mode-of-action of lead compounds and perform experiments to determine cellular targets... Learn about: Phenotypic Screening, Drug Discovery...

...however, patients with serious systemic disease or varying intensity of perceived pain will be excluded. Patients will be characterised using the Brief Pain Inventory... Learn about: Chemotherapy CIPN...

...and insulin secretion. In addition, investigation of analogues of the drug will enable the pharmacophore of any effects to be established, as sulfasalazine...

...clinical trials,as well as exploitation of state-of-the-art patient databases, provides the student with an outstanding platform to establish high-impact... Learn about: IT risk, Human Disease...

...This will be complemented with cell biology in human cells (using CRISPR/Cas9 engineering and advanced microscopy techniques) to investigate their functional... Learn about: Cell Biology, Human cells...

...in human cases of AD, with a view to increasing our understanding of the neuroprotective and potential therapeutic actions of leptin and leptin fragments...

...Disease Rating Scale (UPDRS) [1], which provides a holistic clinical impression of symptom severity, and also to assess rehabilitation [2]. Similarly... Learn about: Physical computing, Clinical PhD, Physical Chemistry...

...ATM. Metformin is recommended as first line oral therapy in Type 2 diabetes (>200 million people world wide) in all international guidelines... Learn about: Nature Genetics...

...malignancies and are a major cause of cancer mortality. Genomic landscaping studies have identified a ’classic subtype’ of SCC, including lung... Learn about: Human solid...

...in SCC from multiple anatomical sites using machine learning and classification to unravel ‘omics’ data and create precision medicine applicable to NHS delivery... Learn about: IT risk...

...trials to enhance our understanding of the mechanisms of Parkinson’s and exploit this knowledge to develop and evaluate novel therapies in the clinic...

...to a less dangerous metabolic steady state which should be easier to maintain, with conventional exercise and diet. In this study we will investigate...

...Transforming growth factor- can act as both a potent tumour suppressor and tumour promoter in a context dependent manner. We have recently discovered...

...and has a fundamental role in the maintenance of cellular homeostasis. Dysregulation of mTOR is associated with a number of human diseases, such as type 2 diabetes...